Blinken called on the president of the Palestinian Authority to end missile launches at Israel.
This is the first high-level contact between the administration of President Joe Biden and the Palestinians.
US Secretary of State Antony Blinken announced on Wednesday night that he had had a conversation with Palestinian Authority President Mahmoud Abas. He called for an end to rocket fire from the Gaza Strip into Israel.
I spoke with President Abbas about the current situation in Jerusalem, the West Bank, and Gaza. I offer my condolences on the loss of life. The US official tweeted, "I emphasized the need to end missile attacks and reduce tensions."
He added that Israelis and Palestinians alike deserve freedom, dignity, security, and prosperity.
This is the first high-level contact between President Joe Biden and the Palestinian Authority.
Washington had earlier announced it would send an ambassador to Israel and the Palestinian territories to request "re-specification" following recent clashes.
Earlier on Wednesday, Biden and Blinken called for "de-escalation" shortly after Israeli Prime Minister Benjamin Netanyahu announced the sending of an ambassador to Israel and the Palestinian territories.
"I had an exchange with BiBi Netanyahu," the president told the White House. I hope the situation will be resolved as soon as possible, but Israel has a right to defend itself when thousands of missiles are fired into its territory, "he said.
Hady Amr, the deputy undersecretary in charge of Israeli and Palestinian affairs, will travel to the region "immediately" to find a way to reach an understanding between the leaders of the two sides and to "end the violence," the head of US diplomacy announced. . Anthony Blinken, to journalists.
"It will require a reduction in confusion on my part and on the part of the president," Blinken said.
Amr will travel to Washington on Wednesday to meet with Israeli and Palestinian leaders, a senior US official said without elaborating.
Blinken also maintained telephone contact with Netanyahu, reiterating his call on all parties to "reduce tensions and end violence.
The Foreign Secretary reiterated his call on all parties to reduce tensions and end the violence, noting that they also "stressed the need for Israelis and Palestinians to live in security" and "freedom.", Enjoy security, success, "and fair democracy."
Blinken stressed that there is a "clear and unequivocal distinction" between Hamas, a terrorist organization that indiscriminately fires rockets - actually targeting civilians - and Israel's response to self-defense.
The latest outbreak of violence, the worst in seven years, has killed at least 74 people and injured hundreds in just two days.