The United States will authorize the mixture of vaccines for the booster dose.

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source: apnews.com

The country's health authorities are expected to vote this week to authorize patients to be given a booster of the COVID 19 vaccine that is not necessarily the same inoculant that was initially placed.

At this point, it is already an open secret. However, at some point this week, federal health regulators in the United States are expected to vote to authorize boosters for COVID vaccines to be placed interchangeably, regardless of who made the vaccine. That is, until now, only those who received the Pfizer vaccine were authorized to receive the third dose of Pfizer. Still, when authorization is given, the patient could receive a booster dose from Moderna or Johnson & Johnson.

Furthermore, it is expected that the FDA (Federal Food and Drug Administration) will simultaneously announce the authorization to combine vaccines with the permission to place boosters to those who were vaccinated with Modera and Johnson & Johnson since until now, only Pfizer has the approval of the reinforcement.

In any case, as it has become known, the FDA is expected to ensure that it is preferable to receive a booster of the vaccine from the same manufacturer, although mixing vaccines is not prohibited. The situation would be unproblematic between Pfizer and Moderna since both are vaccines developed with mRNA technology, which have so far been shown to be somewhat more effective than Johnson & Johnson's more traditional single-dose vaccine.

Preliminary results from a government commission study that included booster vaccines show that an overdose of one of the three vaccines dramatically increases the number of antibodies, especially for those Who had a Johnson & Johnson mono dose. When Pfizer and Modern Booster were added, antibodies increased. If the booster was from Johnson & Johnson, the immune response was not so strong.

One possible problem with this system could be with Modern. The laboratory indicated that the booster was sufficient in its studies if the patient was given half a dose more after the two initial doses. However, if the vaccine mixing system is approved, it would be impossible to count on half doses. In addition, the studies were done with total doses.

The most significant advantage of the vaccine mix has to do with a logistical issue. Putting any of the vaccines makes a mass vaccination in the country for a third dose much easier. It would not be necessary for patients to have to find a vaccination center that has the type of vaccine they need. Let us remember that many of the vaccination centers where people in the country were initially inoculated are now closed; therefore, returning to the same site may not be an option.

In addition, doctors indicate that those patients who had severe side effects with the first doses may feel more confident for a booster if it is from another brand.

At the moment, the recommendation of the CDC (Centers for Disease Control, according to its acronym in English) is that a booster dose be given to those over 65, medical workers, or those whose work expose them more to the virus, as well like any person over 18 years of age with a pre-existing disease that is weaker against COVID-19.